Observation only may be the best medicine for men with early-stage
prostate cancer, suggests a 20-year study published online July 13,
2017, by The New England Journal of Medicine. Early-stage prostate cancer means the cancer is small, confined to the prostate gland, and can only be detected with a biopsy.
Researchers randomly assigned 731 men, average age 67, with localized
prostate cancer to receive either surgery or observation only. At the
20-year follow-up, 62% of the men who had prostate cancer surgery had
died of other causes, while only 7% died from prostate cancer. In
comparison, 67% of the men assigned to observation died from other
causes and 11% from prostate cancer. The absolute differences in
mortality were not significant.
Most striking was how often erectile dysfunction and urinary
incontinence occurred following surgery. For instance, 80% of the
surgery group reported having erectile dysfunction throughout the study,
compared with 40% of the men who were not treated. And more than 40% of
the men who'd had surgery needed to use a daily pad to manage the
urinary incontinence, compared with less than 10% of the observation
group.
The researchers concluded that for most men ages 65 and older with
localized, early-stage prostate cancer, observation might be the
preferred treatment.
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Friday 20 April 2018
Men may want to rethink surgery for early-stage prostate cancer
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