Also known as pyridoxine, vitamin
B6 is a water-soluble vitamin, which means it dissolves in water. It is
not stored by the body, and it is excreted in the urine, so people need
to take in Vitamin B6 every day. It is part of the family of B-complex
vitamins.
Other functions of pyridoxine include protein and glucose metabolism, and the manufacture of hemoglobin.
Hemoglobin is a component of red blood cells. It carries oxygen. Vitamin
B6 is also involved in keeping the lymph nodes, thymus and spleen
healthy.
Potential health benefits of vitamin B6
Vitamin B6 has many functions in the body, and it plays a role in over 100 enzyme reactions.
Brain function
Vitamin B6 may help boost brain performance. A study published in the American Journal of Clinical Nutrition found that people with high concentrations of vitamin B-6 tested better on two measures of memory function.
Vitamin B6 is needed for neuron transmission in the brain.
Researchers from Oxford University in England noted
that taking high doses of B vitamins each day was beneficial for older
people with mild cognitive impairment. The rate at which their brains
shrank fell by 50 percent, potentially lowering their risk of dementia.
Nausea during pregnancy
Research published in the American Journal of Obstetrics and Gynecology concluded that pyridoxine can reduce the severity of nausea in early pregnancy.
However, more high-quality studies are necessary to confirm this. Do not
use more than the recommended dosage if taking a supplement.
Protection from air pollution
A study published in PNAS in 2017 indicated that vitamin B6 may help to
protect against air pollution, by reducing the impact of pollution on
the epigenome.
The researchers hope their findings may lead to new measures to prevent epigenetic changes that can result from exposure air pollution.
With 92 percent of the world's population estimated to be living in
places where pollution limits are higher than the World Health
Organization's upper limit of 10 μg/m3, this could be an important finding when it comes to controlling environmentally triggered disease.
Vitamin B6 is important for many reasons. One is to ensure the normal
functioning of digestive enzymes that break down food, keep the skin
healthy and produce blood products such as red blood cells.
This important vitamin has many other uses, and a deficiency can lead to permanent nerve damage.
How much Vitamin B6 should I have each day?
A number of factors will affect a person's daily requirement for vitamin
B6, because it impacts several aspects of metabolism. The effect on
protein intake has been widely studied.
People who are on high-protein diets may need to take more vitamin B6. They should speak to their doctor.
According to the U.S. Office of Dietary Supplements, the recommended daily requirement for vitamin B6 is:
Age | Male | Female |
0 to 6 months | 0.1 mg | 0.1 mg |
7 to 12 months | 0.3 mg | 0.3 mg |
1 to 3 years | 0.5 mg | 0.5 mg |
4 to 8 years | 0.6 mg | 0.6 mg |
9 to 13 years | 1.0 mg | 1.0 mg |
14 to 18 years | 1.3 mg | 1.3 mg |
19 to 50 years | 1.3 mg | 1.3 mg |
51+ years | 1.7 mg | 1.5 mg |
During pregnancy | - | 1.9 mg |
During lactation | - | 2.0 mg |
Food sources of vitamin B6
Most foods have some vitamin B6. A person with a well-balanced diet
should not have a deficiency, unless they have a physical problem, or
they are taking certain medications.
The following are good sources of B6:
- Chick peas: one cup contains 1.1 milligrams or 55 percent of the recommended daily value (DV)
- Beef liver: 3 ounces contains 0.9 mg, or 45 percent of the DV
- Yellowfin tuna: 3 ounces contains 0.9 mg, or 45 percent of the DV
- Roasted chicken breast: 3 ounces contains 0.5 mg or 25 percent of DV
- One medium banana: contains 0.4 mg or 20 percent of DV
- Tofu: half a cup contains 0.1 mg or 5 percent of DV
Other sources include:
- Avocados
- Brown rice
- Carrots
- Fish
- Fortified cereal
- Hazelnuts
- Milk
- Pork
- Potato
- Seeds
- Soybeans
- Spinach
- Turkey
- Vegetable juice cocktail
- Whole grains
Most foods contain some vitamin B6.
B6 deficiency
Deficiencies are rare, but they may occur if the individual has poor
intestinal absorption or is taking estrogens, corticosteroids,
anticonvulsants, and some other medications.
Long-term, excessive alcohol consumption may eventually result in a B6 deficiency, as can hypothyroidism and diabetes.
Signs and symptoms of vitamin B6 deficiency include:
- Peripheral neuropathy with tingling, numbness, and pain in the hands and feet
- Anemia
- Seizures
- Depression
- Confusion
- Weakened immune system
It can lead to a pellagra-like syndrome, with seborrheic dermatitis, inflammation of the tongue, or glossitis, and inflammation and cracking of the lips, known as cheilosis.
In infants, seizures may persist even after treatment with
anticonvulsants. Other deficiencies, like peripheral neuropathy, can be
permanent.
B6 Supplements
According to the National Institutes of Health (NIH), between 28 and 35 percent of the population in the United States take vitamin supplements containing vitamin B6.
Supplements are available in capsule or tablet form.
The NIH also notes that most people of all ages in the U.S. consume
sufficient B6. Those who are most likely to have low levels of B6 are
those who drink excessive amounts of alcohol, people who are obese, and
pregnant and breastfeeding women.
There is no evidence of any adverse effect from consuming too much vitamin B6 in food.
However, taking between 1 and 6 grams
of oral pyridoxine a day for 12 to 40 months has been shown to cause
severe, progressive sensory neuropathy and a loss of control of body
movement.
The 2015 to 2020 Dietary Guidelines for Americans recommend
that most nutrients should come from foods. They encourage consumption
of a balanced diet with nutrient-dense foods and plenty of dietary
fiber.
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